JWH 149 is a synthetic cannabinoid (CB) which potently binds both the central CB1 receptor (Ki = 5.0 nM) and the peripheral CB2 receptor (Ki = 0.73 nM).
CAS：548461-82-1
分子式：C26H27NO
分子量：369.5
纯度：98%
存储：Store at -20°C

Background:

JWH 149 is a synthetic cannabinoid (CB) which potently binds both the central CB1 receptor (Ki = 5.0 nM) and the peripheral CB2 receptor (Ki = 0.73 nM).[1]? Its physiological properties have not been elucidated. This product is intended for research and forensic applications.

Reference:
[1]. Huffman, J.W., Zengin, G., Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: Steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists. Bioorg. Med. Chem. 13, 89-112 (2005).