Carbosulfan强效抑制CYP3A4,适度抑制CYP1A1/2和CYP2C19。
CAS：55285-14-8
分子式：C20H32N2O3S
分子量：380.54
纯度：98%
存储：Store at -20°C

Background:

Carbosulfan inhibited relatively potently CYP3A4 and moderately CYP1A1/2 and CYP2C19 in pooled HLM (human livers). Carbosulfan activation is predominantly catalyzed in humans by CYP3A4.

[1]. Abass K, et al. Metabolism of carbosulfan II. Human interindividual variability in its in vitro hepatic biotransformation and the identification of the cytochrome P450 isoforms involved. Chem Biol Interact. 2010 May 14;185(3):163-173.