CaerulomycinA(Cerulomycin)是一种联吡啶化合物，能够诱导T细胞的产生。CaerulomycinA能够抑制IFN-γ诱导的STAT1通路，从而增强TGF-β-Smad3信号通路。具有抗真菌和抗细菌活性，可用于自身免疫病的研究。
CAS：21802-37-9
分子式：C12H11N3O2
分子量：229.23
纯度：98%
存储：Store at -20°C

Background:

Caerulomycin A (Cerulomycin) is a bipyridyl compound, induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Antifungal and antibiotic activity, and used in autoimmune diseases[1].

[1]. Gurram RK, et al. Caerulomycin A enhances transforming growth factor-β (TGF-β)-Smad3 protein signaling by suppressing interferon-γ (IFN-γ)-signal transducer and activator of transcription 1 (STAT1) protein signaling to expand regulatory T cells (Tregs). J Biol Chem. 2014 Jun 20;289(25):17515-28.