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Batimastat(BB-94)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Batimastat(BB-94)图片
CAS NO:130370-60-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品名称
BB 94
产品介绍

生物活性

Batimastat (BB-94)是多种基质金属蛋白酶(MMP)的强效合成抑制剂,包括间质胶原酶(IC50 = 3 nM),溶血素(IC50 = 20 nM),Mr 72,000型IV胶原酶(IC50 = 4) nM),92,000型IV胶原酶先生(IC50 = 4 nM)和基质溶素(IC50 = 6 nM)。它是一种低分子量(MW = 478)的肽样胶原蛋白底物类似物,由类似物结合而成,分别与MMP和催化活性锌原子结合在一起。

靶点信息

MMP-1MMP-2MMP-9MMP-7MMP-3
3 nM4 nM4 nM6 nM20 nM

化学数据

目录号A12985
作用机制Inhibitor (抑制剂)
M. Wt477.64
FormulaC23H31N3O4S2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.130370-60-4
SynonymsBB 94
SMILESCC(C)C[C@H]([C@H](CSC1=CC=CS1)C(=O)NO)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)NC

溶解度

In vitro (25°C)DMSO84 mg/mL (175.86 mM)
WaterInsoluble
EthanolInsoluble
In vivo2% DMSO+40% PEG 300+2% Tween 80+ddH2O1 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM20.94 mL104.68 mL209.36 mL
0.5 mM4.19 mL20.94 mL41.87 mL
1 mM2.09 mL10.47 mL20.94 mL
5 mM0.42 mL2.09 mL4.19 mL

*The above data is based on the productmolecular weight 477.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.