Todralazine (hydrochloride) is a β2-adrenergic receptor antagonist with peripheral vasodilator activity.
CAS：3778-76-5
分子式：C11H12N4O2.HCl
分子量：268.7
纯度：98%
存储：Store at -20°C

Background:

Todralazine (hydrochloride) is a β2-adrenergic receptor antagonist with peripheral vasodilator activity. Administration of todralazine (5 uM) to pre-larval zebrafish led to hematopoietic cell expansion and protection from ionizing radiation. It inhibited histone acetylation in vitro and, long-term (4 months), but not short-term (1 month), treatment in mice (3 mg/day) impaired hepatocyte histone acetylation and liver regeneration.