Dehydroascorbicacid，一种可透过血脑屏障的维生素C氧化型，对中风具有有效的脑保护作用。
CAS：490-83-5
分子式：C6H6O6
分子量：174.11
纯度：98%
存储：Store at -20°C

Background:

Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke.

Neuronal injury in ischemic stroke is partly mediated by cytotoxic reactive oxygen species. Although the antioxidant ascorbic acid (AA) or vitamin C does not penetrate the blood-brain barrier (BBB), its oxidized form, dehydroascorbic acid (DHA), enters the brain by means of facilitative transport[1].

[1]. Huang J, et al. Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potentcerebroprotection in experimental stroke. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11720-4.