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IMD 0354
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IMD 0354图片
CAS NO:978-62-1
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
IMD-0354, IMD0354
产品介绍

生物活性

IMD 0354是IκB激酶-β(IKKβ)抑制剂,可阻断NF-κB核易位。

靶点信息

IKKβ

化学数据

目录号A12837
作用机制Inhibitor (抑制剂)
M. Wt383.67
FormulaC15H8ClF6NO2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.978-62-1
SynonymsIMD-0354, IMD0354
SMILESC1=CC(=C(C=C1Cl)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)O

溶解度

In vitro (25°C)DMSO9 mg/mL (23.45 mM)
WaterInsoluble
Ethanol72 mg/mL (187.66 mM)
In vivo2% DMSO+5% Tween 80+0.5% CMC Na2 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM26.06 mL130.32 mL260.64 mL
0.5 mM5.21 mL26.06 mL52.13 mL
1 mM2.61 mL13.03 mL26.06 mL
5 mM0.52 mL2.61 mL5.21 mL

*The above data is based on the productmolecular weight 383.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.