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IWP-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IWP-2图片
CAS NO:686770-61-6
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
IWP 2,IWP2
产品介绍

生物活性

IWP-2是Porcn功能的灭活剂和Wnt生成的抑制剂,无细胞试验中IC50为27 nM,并阻止β-catenin的积累。Wnt/b-catenin途径维持使干细胞保持多能性的转录程序。

靶点信息

Wnt (Cell-free assay)
27 nM

化学数据

目录号A12707
作用机制Inhibitor (抑制剂)
M. Wt466.6
FormulaC22H18N4O2S3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.686770-61-6
SynonymsIWP 2,IWP2
SMILESCC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4

溶解度

In vitroDMSOInsoluble
WaterInsoluble
EthanolDMF: 48 mg/mL (102.87 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM21.43 mL107.16 mL214.32 mL
0.5 mM4.29 mL21.43 mL42.86 mL
1 mM2.14 mL10.72 mL21.43 mL
5 mM0.43 mL2.14 mL4.29 mL

*The above data is based on the productmolecular weight 466.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.