L-689502是一个有效的HIV-1蛋白酶(HIV-lprotease)抑制剂，其IC50值为1nM。
CAS：138483-63-3
分子式：C39H51N3O7
分子量：673.84
纯度：98%
存储：Store at -20°C

Background:

L-689502 is a potent inhibitor of HIV-l protease with an IC50 of 1 nM.

Both L694746 and L-689502 inhibit HIV-l ptotease activity in a concentration-dependent manner. Pepstatin is much less potent than either compound exhibiting an IC50 of 2 μM. L694746 is as potent as L-689502 in inhibiting the HIV-l protease despite being structurally different from L-689502[1].

[1]. Lingham RB, et al. HIV-1 protease inhibitory activity of L-694,746, a novel metabolite of L-689,502. Biochem Biophys Res Commun. 1991 Dec 31;181(3):1456-61.