Verteporfin

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Verteporfin

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

129497-78-5

包装与价格：

包装	价格(元)
5mg	电议
10mg	电议
25mg	电议
50mg	电议
10mM * 1mL in DMSO	电议

产品名称

Visudyne, DB00460??CL 318,952??Benzoporphyrin D??Bpd-MA??AIDS350621??AIDS-350621??Benzoporphyrin derivative monoacid ring A.

产品介绍

生物活性

Verteporfin是抑制TEAD-YAP缔合和YAP诱导的肝过度生长的小分子。它也是一种有效的第二代光敏剂，衍生自卟啉。

靶点信息

VDA (Endothelial cells)

化学数据

目录号	A12658
作用机制	Inhibitor (抑制剂)
M. Wt	718.79
Formula	C41H42N4O8
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	129497-78-5
Synonyms	Visudyne, DB00460??CL 318,952??Benzoporphyrin D??Bpd-MA??AIDS350621??AIDS-350621??Benzoporphyrin derivative monoacid ring A.
SMILES	O=C(O)CCC1=C(C)C(/C=C2C(C=C)=C(C)/C(N/2)=C/3)=N/C1=C\C(N4)=C(CCC(OC)=O)C(C)=C4/C=C5[C@]6(C)[C@H](C(OC)=O)C(C(OC)=O)=CC=C6C3=N/5

溶解度

In vitro	DMSO	89 mg/mL (123.82 mM)
	Water	Insoluble
	Ethanol	Insoluble
<1 mg/ml means slightly soluble or insoluble. Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	13.91 mL	69.56 mL	139.12 mL
0.5 mM	2.78 mL	13.91 mL	27.82 mL
1 mM	1.39 mL	6.96 mL	13.91 mL
5 mM	0.28 mL	1.39 mL	2.78 mL

*The above data is based on the productmolecular weight 718.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.