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S1RA(E-52862)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
S1RA(E-52862)图片
CAS NO:878141-96-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品名称
E52862, E 52862, MR390
MR 390
MR-390
产品介绍

生物活性

S1RA是一种选择性sigma-1受体拮抗剂,据报道其结合亲和力为Ki = 17.0±7.0 nM,对sigma-2受体具有选择性,并且对其他170种受体,酶,转运蛋白和离子通道具有选择性。

化学数据

目录号A12504
作用机制Antagonist (拮抗剂)
M. Wt337.42
FormulaC20H23N3O2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.878141-96-9
SynonymsE52862, E 52862, MR390; MR 390; MR-390
SMILESCC1=CC(=NN1C2=CC3=CC=CC=C3C=C2)OCCN4CCOCC4

溶解度

In vitroDMSO63 mg/mL (186.71 mM)
Water63 mg/mL (186.71 mM)
Ethanol18 mg/mL (53.34 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM29.64 mL148.18 mL296.37 mL
0.5 mM5.93 mL29.64 mL59.27 mL
1 mM2.96 mL14.82 mL29.64 mL
5 mM0.59 mL2.96 mL5.93 mL

*The above data is based on the productmolecular weight 337.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.