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Empagliflozin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Empagliflozin图片
CAS NO:864070-44-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
10mM * 1mL in DMSO电议

产品介绍

生物活性

Empagliflozin是一种有效的选择性葡萄糖钠共转运蛋白-2抑制剂,目前正在开发中,用于治疗2型糖尿病。

靶点信息

SGLT2SGLT5SGLT6SGLT1SGLT4
3.1 nM1.1 μM2 μM8.3 μM11 μM

化学数据

目录号A12440
M. Wt450.91
FormulaC23H27ClO7
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.864070-44-0
SMILESC1COC[C@H]1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl

溶解度

In vitro (25°C)DMSO88 mg/mL (195.15 mM)
WaterInsoluble
EthanolInsoluble
In vivo15% Captisol14 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM22.18 mL110.89 mL221.77 mL
0.5 mM4.44 mL22.18 mL44.35 mL
1 mM2.22 mL11.09 mL22.18 mL
5 mM0.44 mL2.22 mL4.44 mL

*The above data is based on the productmolecular weight 450.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.