生物活性
TCN 201是对NR1/NR2A相对于含NR1/NR2B的受体具有选择性的NMDA受体拮抗剂。
化学数据
| 目录号 | A11947 |
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 461.89 |
| Formula | C21H17ClFN3O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 852918-02-6 |
| Synonyms | TCN-201 |
| SMILES | C1=CC=C(C=C1)C(=O)NNC(=O)C2=CC=C(C=C2)CNS(=O)(=O)C3=CC(=C(C=C3)F)Cl |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 21.65 mL | 108.25 mL | 216.5 mL |
| 0.5 mM | 4.33 mL | 21.65 mL | 43.3 mL |
| 1 mM | 2.17 mL | 10.83 mL | 21.65 mL |
| 5 mM | 0.43 mL | 2.17 mL | 4.33 mL |
*The above data is based on the productmolecular weight 461.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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