Dopamineserotoninantagonist-1是dopamine和serotonin受体拮抗剂，对多巴胺D1，D2，D4和血清素S2A，S2C，S3的Ki值分别为200，2500，420，39，84，40nM。
CAS：1977-07-7
分子式：C18H20N4
分子量：292.38
纯度：98%
存储：Store at -20°C

Background:

Dopamine serotonin antagonist-1 is a dual dopamine and serotonin receptor antagonist with Kis of 200, 2500, 420, 39, 84, 40 nM for dopamine D1, D2,D4, and serotonin S2A, S2C, S3, respectively.

[1]. Phillips ST, et al. Binding of 5H-dibenzo[b,e][1,4]diazepine and chiral 5H-dibenzo[a,d]cycloheptene analogues of clozapine to dopamine and serotonin receptors. J Med Chem. 1994 Aug 19;37(17):2686-96.