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Pravastatin sodium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pravastatin sodium图片
CAS NO:81131-70-6
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
250mg电议
10mM * 1mL in DMSO电议

产品名称
Eptastatin sodium
产品介绍

生物活性

Pravastatin sodium是3-羟基-3-甲基辅酶A(HMG-CoA)还原酶的水溶性竞争性抑制剂。有效阻断体内胆固醇合成(Ki?1 nM)并显示出心脏保护特性。

靶点信息

HMG-CoA reductase
5.6 μM

化学数据

目录号A11912
作用机制Inhibitor (抑制剂)
M. Wt446.51
FormulaC23H35NaO7
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.81131-70-6
SynonymsEptastatin sodium
SMILESCC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)[O-])O)O)O.[Na+]

溶解度

In vitroDMSO79 mg/mL (176.92 mM)
Water79 mg/mL (176.92 mM)
Ethanol11 mg/mL (24.63 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM22.4 mL111.98 mL223.96 mL
0.5 mM4.48 mL22.4 mL44.79 mL
1 mM2.24 mL11.2 mL22.4 mL
5 mM0.45 mL2.24 mL4.48 mL

*The above data is based on the productmolecular weight 446.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.