生物活性
AM 580是视黄酸的类似物，可作为选择性RARα激动剂。
化学数据
| 目录号 | A11792 |
| 作用机制 | Agonist (激动剂) |
| M. Wt | 351.4 |
| Formula | C22H25NO3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 102121-60-8 |
| Synonyms | AM580, AM-580, CD 336, NSC 608001, Ro 40-6055 |
| SMILES | CC1(CCC(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)(C)C)C |
溶解度
| In vitro | DMSO | 66 mg/mL (187.8 mM) |
| Water | Insoluble |
| Ethanol | 23 mg/mL (65.44 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 28.46 mL | 142.29 mL | 284.58 mL |
| 0.5 mM | 5.69 mL | 28.46 mL | 56.92 mL |
| 1 mM | 2.85 mL | 14.23 mL | 28.46 mL |
| 5 mM | 0.57 mL | 2.85 mL | 5.69 mL |
*The above data is based on the productmolecular weight 351.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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