生物活性
LX 1606 (Telotristat)是一种口服生物可利用的小分子色氨酸羟化酶（TPH）抑制剂，具有潜在的抗血清素活性。
化学数据
| 目录号 | A11785 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 575.0 |
| Formula | C27H26ClF3N6O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 1033805-22-9 |
| Synonyms | LX1606 |
| SMILES | CCOC(=O)[C@H](CC1=CC=C(C=C1)C2=CC(=NC(=N2)N)O[C@H](C3=C(C=C(C=C3)Cl)N4C=CC(=N4)C)C(F)(F)F)N |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 17.39 mL | 86.96 mL | 173.91 mL |
| 0.5 mM | 3.48 mL | 17.39 mL | 34.78 mL |
| 1 mM | 1.74 mL | 8.7 mL | 17.39 mL |
| 5 mM | 0.35 mL | 1.74 mL | 3.48 mL |
*The above data is based on the productmolecular weight 575.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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