| CAS NO: | 111358-88-4 |
| 包装: | 1mg |
| 规格: | 98% |
| 市场价: | 2516元 |
| 分子量: | 439.46 |
Background:
Potent JAK2, FLT3 and TrkA inhibitor (IC50values are 0.9, 3 and < 25 nM respectively) that prevents STAT5 phosphorylation (IC50= 20 - 30 nM). Exhibits antiproliferative activityin vitro(IC50= 30 - 100 nM in HEL92.1.7 cells) and is effective against myeloproliferative disordersin vivo.
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