生物活性
Duloxetine是5-羟色胺-去甲肾上腺素再摄取抑制剂(SNRI)。它对重度抑郁症和广泛性焦虑症(GAD)有效。
化学数据
| 目录号 | A11705 |
| M. Wt | 297.41 |
| Formula | C18H19NOS |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 116539-60-7 |
| Synonyms | Cymbalta, Ariclaim |
| SMILES | CNCC[C@H](C1=CC=CS1)OC2=CC=CC3=CC=CC=C32 |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 33.62 mL | 168.12 mL | 336.24 mL |
| 0.5 mM | 6.72 mL | 33.62 mL | 67.25 mL |
| 1 mM | 3.36 mL | 16.81 mL | 33.62 mL |
| 5 mM | 0.67 mL | 3.36 mL | 6.72 mL |
*The above data is based on the productmolecular weight 297.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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