生物活性
Genipin是garden子果实提取物中的一种化学化合物。Genipin是用于蛋白质，胶原蛋白，明胶和壳聚糖交联的出色天然交联剂。此外，京尼平可用作药物递送的调节剂，garden子蓝色颜料制备的原料以及生物碱合成的中间体。体外实验表明，Genipin阻断了酶解偶联蛋白2的作用。
靶点信息
化学数据
| 目录号 | A11677 |
| M. Wt | 226.23 |
| Formula | C11H14O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 6902-77-8 |
| SMILES | COC(=O)C1=CO[C@H]([C@H]2[C@@H]1CC=C2CO)O |
溶解度
| In vitro (25°C) | DMSO | 42 mg/mL (185.65 mM) |
| Water | Insoluble |
| Ethanol | 42 mg/mL (185.65 mM) |
| In vivo | 5% DMSO+30% PEG 300+ddH2O | 19 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 44.2 mL | 221.01 mL | 442.03 mL |
| 0.5 mM | 8.84 mL | 44.2 mL | 88.41 mL |
| 1 mM | 4.42 mL | 22.1 mL | 44.2 mL |
| 5 mM | 0.88 mL | 4.42 mL | 8.84 mL |
*The above data is based on the productmolecular weight 226.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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