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SU-5402
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SU-5402图片
CAS NO:215543-92-3
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品名称
SU5402, SU 5402
产品介绍

生物活性

SU-5402是有效且选择性的血管内皮生长因子受体(VEGFR)和成纤维细胞生长因子受体(FGFR)抑制剂(在VEGFR2, FGFR1, PDGFRβ和EGFR处IC50值分别为0.02、0.03、0.51和> 100μM)。

靶点信息

VEGFR2FGFR1PDGFRβ
20 nM30 nM510 nM

化学数据

目录号A11558
作用机制Inhibitor (抑制剂)
M. Wt296.32
FormulaC17H16N2O3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.215543-92-3
SynonymsSU5402, SU 5402
SMILESCC1=CNC(=C1CCC(=O)O)/C=C\2/C3=CC=CC=C3NC2=O

溶解度

In vitroDMSO54 mg/mL (182.23 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM33.75 mL168.74 mL337.47 mL
0.5 mM6.75 mL33.75 mL67.49 mL
1 mM3.37 mL16.87 mL33.75 mL
5 mM0.67 mL3.37 mL6.75 mL

*The above data is based on the productmolecular weight 296.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.