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LDN193189 HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LDN193189 HCl图片
CAS NO:1062368-62-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品名称
LDN 193189
产品介绍

生物活性

LDN193189 HCl是ldn193189的盐酸盐。LDN193189是一种高效的小分子BMP抑制剂,可抑制BMP I型受体ALK2(IC50:5 nM),ALK3(IC50:30 nM)和ALK6(TGFβ1/ BMP信号转导)以及随后的SMAD磷酸化。

靶点信息

ALK2 (C2C12 cells)ALK3 (C2C12 cells)
5 nM30 nM

化学数据

目录号A11478
M. Wt442.94
FormulaC25H22N6.HCl
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1062368-62-0
SynonymsLDN 193189
SMILESC1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3.Cl.Cl.Cl.Cl

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM22.58 mL112.88 mL225.76 mL
0.5 mM4.52 mL22.58 mL45.15 mL
1 mM2.26 mL11.29 mL22.58 mL
5 mM0.45 mL2.26 mL4.52 mL

*The above data is based on the productmolecular weight 442.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.