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GNF 2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GNF 2图片
CAS NO:778270-11-4
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品名称
GNF2,GNF-2
产品介绍

生物活性

GNF 2是一种Bcr-abl抑制剂,在表达Bcr-abl的细胞中抑制增殖并诱导凋亡。

靶点信息

Bcr-Abl (SUP-B15 cell line)Bcr-Abl (K562 cell line)
268 nM273 nM

化学数据

目录号A11439
作用机制Inhibitor (抑制剂)
M. Wt374.3
FormulaC18H13F3N4O2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.778270-11-4
SynonymsGNF2,GNF-2
SMILESC1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F

溶解度

In vitroDMSO67 mg/mL (178.99 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM26.72 mL133.58 mL267.17 mL
0.5 mM5.34 mL26.72 mL53.43 mL
1 mM2.67 mL13.36 mL26.72 mL
5 mM0.53 mL2.67 mL5.34 mL

*The above data is based on the productmolecular weight 374.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.