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Ganetespib(STA-9090)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ganetespib(STA-9090)图片
CAS NO:888216-25-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品名称
STA9090
产品介绍

生物活性

Ganetespib (STA-9090)是Hsp90的有效合成小分子抑制剂,Hsp90是一种伴侣蛋白,对于某些其他蛋白的功能至关重要,这些蛋白可驱动许多不同类型的癌症的生长,增殖和存活。

靶点信息

HSP90 (OSA 8 cells)
4 nM

化学数据

目录号A11402
作用机制Inhibitor (抑制剂)
M. Wt364.4
FormulaC20H20N4O3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.888216-25-9
SynonymsSTA9090
SMILESCC(C)C1=CC(=C2NNC(=O)N2C3=CC4=C(C=C3)N(C=C4)C)C(=O)C=C1O

溶解度

In vitro (25°C)DMSO37 mg/mL (101.53 mM)
WaterInsoluble
EthanolInsoluble
In vivo5% DMSO+45% PEG 300+ddH2O10 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM27.44 mL137.21 mL274.42 mL
0.5 mM5.49 mL27.44 mL54.88 mL
1 mM2.74 mL13.72 mL27.44 mL
5 mM0.55 mL2.74 mL5.49 mL

*The above data is based on the productmolecular weight 364.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.