您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > E-7050(Golvatinib)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
E-7050(Golvatinib)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
E-7050(Golvatinib)图片
CAS NO:928037-13-2
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品介绍

生物活性

E-7050 (Golvatinib)是具有潜在抗肿瘤活性的c-Met(肝细胞生长因子受体)和VEGFR-2(血管内皮生长因子受体-2)酪氨酸激酶的口服生物可利用双重激酶抑制剂。

靶点信息

c-MetVEGFR2
14 nM16 nM

化学数据

目录号A11396
M. Wt633.69
FormulaC33H37F2N7O4
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.928037-13-2
SMILESCN1CCN(CC1)C2CCN(CC2)C(=O)NC3=NC=CC(=C3)OC4=CC(=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F

溶解度

In vitro (25°C)DMSO18 mg/mL (28.4 mM)
WaterInsoluble
EthanolInsoluble
In vivo30% propylene glycol, 5% Tween 80, 65% D5W28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM15.78 mL78.9 mL157.81 mL
0.5 mM3.16 mL15.78 mL31.56 mL
1 mM1.58 mL7.89 mL15.78 mL
5 mM0.32 mL1.58 mL3.16 mL

*The above data is based on the productmolecular weight 633.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.