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Emricasan
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Emricasan图片
CAS NO:254750-02-2
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品名称
IDN-6556, IDN6556, IDN 6556, PF 03491390, PF-03491390, PF03491390
产品介绍

生物活性

Emricasan is a first-in-class caspase inhibitor in clinical trials for the treatment of liver diseases.

靶点信息

caspase

化学数据

目录号A11394
作用机制Inhibitor (抑制剂)
M. Wt569.5
FormulaC26H27F4N3O7
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.254750-02-2
SynonymsIDN-6556, IDN6556, IDN 6556, PF 03491390, PF-03491390, PF03491390
SMILESCC(C(=O)NC(CC(=O)O)C(=O)COC1=C(C(=CC(=C1F)F)F)F)NC(=O)C(=O)NC2=CC=CC=C2C(C)(C)C

溶解度

In vitroDMSO97 mg/mL (170.32 mM)
WaterInsoluble
Ethanol97 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM17.56 mL87.8 mL175.59 mL
0.5 mM3.51 mL17.56 mL35.12 mL
1 mM1.76 mL8.78 mL17.56 mL
5 mM0.35 mL1.76 mL3.51 mL

*The above data is based on the productmolecular weight 569.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.