生物活性
Boceprevir (SCH-503034)是一种蛋白酶抑制剂，可用于治疗C型肝炎基因型1。
化学数据
| 目录号 | A11332 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 519.7 |
| Formula | C27H45N5O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 394730-60-0 |
| Synonyms | EBP 520, SCH 503034 |
| SMILES | CC1([C@@H]2[C@H]1[C@H](N(C2)C(=O)[C@H](C(C)(C)C)NC(=O)NC(C)(C)C)C(=O)NC(CC3CCC3)C(=O)C(=O)N)C |
溶解度
| In vitro | DMSO | 90 mg/mL (173.18 mM) |
| Water | Insoluble |
| Ethanol | 90 mg/mL (173.18 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 19.24 mL | 96.21 mL | 192.42 mL |
| 0.5 mM | 3.85 mL | 19.24 mL | 38.48 mL |
| 1 mM | 1.92 mL | 9.62 mL | 19.24 mL |
| 5 mM | 0.38 mL | 1.92 mL | 3.85 mL |
*The above data is based on the productmolecular weight 519.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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