生物活性
BMS-345541 HCl是一种细胞可渗透且高度选择性的IKB激酶（IKK）抑制剂，可在酶的变构位点结合并阻断小鼠中NF-kB依赖性转录。
化学数据
| 目录号 | A11318 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 291.8 |
| Formula | C14H18ClN5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 547757-23-3 |
| Synonyms | BMS345541, BMS-345541 |
| SMILES | CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN.Cl |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 34.27 mL | 171.35 mL | 342.7 mL |
| 0.5 mM | 6.85 mL | 34.27 mL | 68.54 mL |
| 1 mM | 3.43 mL | 17.14 mL | 34.27 mL |
| 5 mM | 0.69 mL | 3.43 mL | 6.85 mL |
*The above data is based on the productmolecular weight 291.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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