您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > FG-4592(Roxadustat)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
FG-4592(Roxadustat)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FG-4592(Roxadustat)图片
CAS NO:808118-40-3
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
FG4592, ASP1517
产品介绍

生物活性

FG-4592 (Roxadustat)是一种用于CKD贫血的新型缺氧诱导因子脯氨酰羟化酶抑制剂。

靶点信息

HIF α prolyl hydroxylase (Cell-free assay)

化学数据

目录号A11237
作用机制Inhibitor (抑制剂)
M. Wt352.3
FormulaC19H16N2O5
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.808118-40-3
SynonymsFG4592, ASP1517
SMILESCC1=NC(=C(C2=C1C=C(C=C2)OC3=CC=CC=C3)O)C(=O)NCC(=O)O

溶解度

In vitro (25°C)DMSO62 mg/mL (175.96 mM)
WaterInsoluble
EthanolInsoluble
In vivo5% DMSO+40% PEG 300+5% Tween 80+50% ddH2O9 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM28.38 mL141.92 mL283.85 mL
0.5 mM5.68 mL28.38 mL56.77 mL
1 mM2.84 mL14.19 mL28.38 mL
5 mM0.57 mL2.84 mL5.68 mL

*The above data is based on the productmolecular weight 352.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.