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5-hydroxymethyl tolterodine(PNU 200577)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5-hydroxymethyl tolterodine(PNU 200577)图片
CAS NO:207679-81-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
(R)-5-Hydroxymethyl Tolterodine
产品介绍

生物活性

5-hydroxymethyl tolterodine (PNU 200577)是托特罗定的代谢产物,tolterodine是一种用于治疗尿失禁的毒蕈碱受体拮抗剂。

靶点信息

mAChR
0.84 nM(Kb)

化学数据

目录号A11166
作用机制Antagonist (拮抗剂)
M. Wt341.49
FormulaC22H31NO2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.207679-81-0
Synonyms(R)-5-Hydroxymethyl tolterodine
SMILESCC(C)N(CC[C@H](C1=CC=CC=C1)C2=C(C=CC(=C2)CO)O)C(C)C

溶解度

In vitroDMSO60 mg/mL (175.69 mM)
WaterInsoluble
Ethanol60 mg/mL (175.69 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM29.28 mL146.42 mL292.83 mL
0.5 mM5.86 mL29.28 mL58.57 mL
1 mM2.93 mL14.64 mL29.28 mL
5 mM0.59 mL2.93 mL5.86 mL

*The above data is based on the productmolecular weight 341.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.