生物活性
Brefeldin A阻断ADP-核糖基化因子与高尔基体的结合并抑制GDP-GTP交换。
靶点信息
化学数据
| 目录号 | A11156 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 280.4 |
| Formula | C16H24O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 20350-15-6 |
| Synonyms | Brefeldin-A |
| SMILES | C[C@H]1CCC/C=C/[C@@H]2C[C@@H](C[C@H]2[C@@H](/C=C/C(=O)O1)O)O |
溶解度
| In vitro | DMSO | 4 mg/mL (14.26 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 35.66 mL | 178.32 mL | 356.63 mL |
| 0.5 mM | 7.13 mL | 35.66 mL | 71.33 mL |
| 1 mM | 3.57 mL | 17.83 mL | 35.66 mL |
| 5 mM | 0.71 mL | 3.57 mL | 7.13 mL |
*The above data is based on the productmolecular weight 280.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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