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Vicriviroc Malate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Vicriviroc Malate图片
CAS NO:541503-81-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍

生物活性

Vicriviroc Malate是CCR5拮抗剂,也是HIV-1进入靶细胞的有效抑制剂,对HIV分离株的平均IC50 = 0.46 nM,IC50 = 1?10 nM(n = 52)。

化学数据

目录号A10971
作用机制Antagonist (拮抗剂)
M. Wt667.7
FormulaC28H38F3N5O2.C4H6O5
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.541503-81-5
SMILESC[C@H]1CN(CCN1[C@@H](COC)C2=CC=C(C=C2)C(F)(F)F)C3(CCN(CC3)C(=O)C4=C(N=CN=C4C)C)C.C(C(C(=O)O)O)C(=O)O

溶解度

In vitroDMSO121 mg/mL (181.21 mM)
Water34 mg/mL (50.92 mM)
Ethanol121 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM14.98 mL74.88 mL149.77 mL
0.5 mM3 mL14.98 mL29.95 mL
1 mM1.5 mL7.49 mL14.98 mL
5 mM0.3 mL1.5 mL3 mL

*The above data is based on the productmolecular weight 667.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.