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Tigecycline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tigecycline图片
CAS NO:220620-09-7
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
Tygacil, GAR-936, WAY-GAR-936, TBG-MINO
产品介绍

生物活性

Tigecycline具有抑菌作用,是一种蛋白质合成抑制剂,可与细菌的30S核糖体亚基结合,从而在原核翻译过程中阻止氨酰tRNA进入核糖体的A位点。

化学数据

目录号A10933
M. Wt585.7
FormulaC29H39N5O8
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.220620-09-7
SynonymsTygacil, GAR-936, WAY-GAR-936, TBG-MINO
SMILESCC(C)(C)NCC(=O)NC1=C(C2=C(C[C@H]3C[C@H]4[C@@H](C(=O)C(=C([C@]4(C(=O)C3=C2O)O)O)C(=O)N)N(C)C)C(=C1)N(C)C)O

溶解度

In vitro (25°C)DMSO86 mg/mL (146.85 mM)
Water86 mg/mL (146.85 mM)
EthanolInsoluble
In vivoSaline28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM17.07 mL85.37 mL170.74 mL
0.5 mM3.41 mL17.07 mL34.15 mL
1 mM1.71 mL8.54 mL17.07 mL
5 mM0.34 mL1.71 mL3.41 mL

*The above data is based on the productmolecular weight 585.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.