生物活性
Ranolazine是部分脂肪酸氧化抑制剂，可将ATP的生产从脂肪酸转变为氧效率更高的碳水化合物氧化。
靶点信息
化学数据
| 目录号 | A10780 |
| M. Wt | 427.5 |
| Formula | C24H33N3O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 95635-55-5 |
| Synonyms | Ranexa |
| SMILES | CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC(COC3=CC=CC=C3OC)O |
溶解度
| In vitro | DMSO | 77 mg/mL (180.1 mM) |
| Water | Insoluble |
| Ethanol | 18 mg/mL (42.09 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 23.39 mL | 116.96 mL | 233.92 mL |
| 0.5 mM | 4.68 mL | 23.39 mL | 46.78 mL |
| 1 mM | 2.34 mL | 11.7 mL | 23.39 mL |
| 5 mM | 0.47 mL | 2.34 mL | 4.68 mL |
*The above data is based on the productmolecular weight 427.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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