生物活性
Pyroxamide (NSC 696085)是亲和纯化的HDAC1的有效抑制剂，可导致乙酰化核心组蛋白在用该试剂培养的MEL细胞中积累。
化学数据
| 目录号 | A10764 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 265.3 |
| Formula | C13H19N3O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 382180-17-8 |
| Synonyms | NSC-696085,NSC696085 |
| SMILES | C1=CC(=CN=C1)NC(=O)CCCCCCC(=O)NO |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 37.69 mL | 188.47 mL | 376.93 mL |
| 0.5 mM | 7.54 mL | 37.69 mL | 75.39 mL |
| 1 mM | 3.77 mL | 18.85 mL | 37.69 mL |
| 5 mM | 0.75 mL | 3.77 mL | 7.54 mL |
*The above data is based on the productmolecular weight 265.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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