生物活性
Oridonin (Isodonol)是一种从鼠李木中分离出来的Entkaurane二萜类化合物，是一种重要的传统中草药。
化学数据
| 目录号 | A10675 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 364.4 |
| Formula | C20H28O6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 28957-04-2 |
| Synonyms | Isodonol |
| SMILES | CC1(CCC([C@@]23C1[C@@H](C([C@@]45C2CC[C@H](C4O)C(=C)C5=O)(OC3)O)O)O)C |
溶解度
| In vitro (25°C) | DMSO | 69 mg/mL (189.33 mM) |
| Water | Insoluble |
| Ethanol | 27 mg/mL (74.09 mM) |
| In vivo | 5% DMSO+20%PEG 300+ddH2O | 11.8 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 27.44 mL | 137.21 mL | 274.42 mL |
| 0.5 mM | 5.49 mL | 27.44 mL | 54.88 mL |
| 1 mM | 2.74 mL | 13.72 mL | 27.44 mL |
| 5 mM | 0.55 mL | 2.74 mL | 5.49 mL |
*The above data is based on the productmolecular weight 364.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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