CAS NO: | 430458-66-5 |
包装: | 50mg, 100mg, 250mg |
规格: | ≥98% |
MMRi64 is a novel specific inhibitor of Mdm2-MdmX E3 ligase activity toward Mdm2 and p53 substrates, potently inducing p53-dependent and p53-independent apoptosis in lymphoma cells. References: Wu W, Xu C, Ling X, Fan C, Buckley BP, Chernov MV, Ellis L, Li F, Munoz IG, Wang X. Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells. Cell Death Dis. 2015 Dec 31;6:e2035. doi: 10.1038/cddis.2015.358. PubMed PMID: 26720344; PubMed Central PMCID: PMC4720891.
纯度:≥98%
CAS:430458-66-5