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MMRi64
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:430458-66-5
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

MMRi64 is a novel specific inhibitor of Mdm2-MdmX E3 ligase activity toward Mdm2 and p53 substrates, potently inducing p53-dependent and p53-independent apoptosis in lymphoma cells. References: Wu W, Xu C, Ling X, Fan C, Buckley BP, Chernov MV, Ellis L, Li F, Munoz IG, Wang X. Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells. Cell Death Dis. 2015 Dec 31;6:e2035. doi: 10.1038/cddis.2015.358. PubMed PMID: 26720344; PubMed Central PMCID: PMC4720891.

纯度:≥98%

CAS:430458-66-5