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MC1568
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MC1568图片
CAS NO:852475-26-4
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
MC-1568
产品介绍

生物活性

MC1568是HDAC抑制剂的成员,它通过修饰细胞周期的各种重要基因的基因表达(主要在G1期)来抑制II类组蛋白脱乙酰基酶,从而导致细胞凋亡导致乳腺癌细胞死亡。

靶点信息

HD1-A (Maize) (Cell-free assay)HD1-B (Maize) (Cell-free assay)
100 nM3.4 μM

化学数据

目录号A10560
作用机制Inhibitor (抑制剂)
M. Wt314.3
FormulaC17H15FN2O3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.852475-26-4
SynonymsMC-1568
SMILESCN1C=C(C=C1/C=C/C(=O)NO)/C=C/C(=O)C2=CC(=CC=C2)F

溶解度

In vitro (25°C)DMSO12 mg/mL (38.18 mM)
WaterInsoluble
EthanolInsoluble
In vivo0.5% CMC4 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM31.82 mL159.08 mL318.17 mL
0.5 mM6.36 mL31.82 mL63.63 mL
1 mM3.18 mL15.91 mL31.82 mL
5 mM0.64 mL3.18 mL6.36 mL

*The above data is based on the productmolecular weight 314.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.