Background:

Salicylanilide demonstrates a wide range of biological activities including antiviral potency which can inhibit HIV virusby targeting HIV-1 integrase or reverse transcriptase.

Some Salicylanilides and salicylamides could inhibit HIV virus by targeting of HIV-1 integrase or reverse transcriptase. Hepatitis C virus is another virus, which can be potentially afflicted by Salicylanilides on the level of two enzymes-NS3 protease and NS5B RNA polymerase[1].

参考文献:
[1]. Krátky M, et al. Antiviral activity of substituted salicylanilides--a review. Mini Rev Med Chem. 2011 Oct;11(11):956-67.