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Lenalidomide(CC-5013)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Lenalidomide(CC-5013)图片
CAS NO:191732-72-6
包装与价格:
包装价格(元)
50mg电议
100mg电议
250mg电议
500mg电议
10mM * 1mL in DMSO电议

产品名称
CC-5013, Revlimid
产品介绍

生物活性

Lenalidomide (CC-5013)是Thalidomide的衍生物。在体外,Lenalidomide具有三种主要活性:直接抗肿瘤作用、抑制肿瘤细胞的微环境支持和免疫调节作用。它通过抑制骨髓基质细胞支持、抗血管生成和抗破骨细胞生成作用以及免疫调节活性直接和间接诱导肿瘤细胞凋亡。

化学数据

目录号A10522
作用机制Inducer (诱导剂)
M. Wt259.3
FormulaC13H13N3O3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.191732-72-6
SynonymsCC-5013, Revlimid
SMILESC1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N

溶解度

In vitro (25°C)DMSO46 mg/mL (177.43 mM)
WaterInsoluble
EthanolInsoluble
In vivo5% DMSO+40%PEG 300+5%Tween80+ddH2O9 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM38.57 mL192.83 mL385.65 mL
0.5 mM7.71 mL38.57 mL77.13 mL
1 mM3.86 mL19.28 mL38.57 mL
5 mM0.77 mL3.86 mL7.71 mL

*The above data is based on the productmolecular weight 259.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.