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JNJ-38877605
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
JNJ-38877605图片
CAS NO:943540-75-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
JNJ38877605
产品介绍

生物活性

JNJ-38877605是一种ATP竞争性的c-Met抑制剂,从而抑制c-Met磷酸化并破坏c-Met信号转导途径。

化学数据

目录号A10493
作用机制Inhibitor (抑制剂)
M. Wt377.4
FormulaC19H13F2N7
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.943540-75-8
SynonymsJNJ38877605
SMILESCN1C=C(C=N1)C2=NN3C(=NN=C3C(C4=CC5=C(C=C4)N=CC=C5)(F)F)C=C2

溶解度

In vitro (25°C)DMSO33 mg/mL (87.45 mM)
WaterInsoluble
EthanolInsoluble
In vivo30% propylene glycol, 5% Tween 80, 65% D5W28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM26.5 mL132.49 mL264.97 mL
0.5 mM5.3 mL26.5 mL52.99 mL
1 mM2.65 mL13.25 mL26.5 mL
5 mM0.53 mL2.65 mL5.3 mL

*The above data is based on the productmolecular weight 377.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.