生物活性
伊拉地平是二氢吡啶类钙通道阻滞剂。
靶点信息
化学数据
| 目录号 | A10487 |
| 作用机制 | Blocker (阻断剂) |
| M. Wt | 371.4 |
| Formula | C19H21N3O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 75695-93-1 |
| Synonyms | DynaCirc, Prescal, PN-200-110, Clivoten, Esradin |
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC3=NON=C32)C(=O)OC |
溶解度
| In vitro (25°C) | DMSO | 71 mg/mL (191.17 mM) |
| Water | Insoluble |
| Ethanol | Warmed: 71 mg/mL (191.17 mM) |
| In vivo | 2% DMSO+corn oil | 9 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 26.93 mL | 134.63 mL | 269.25 mL |
| 0.5 mM | 5.39 mL | 26.93 mL | 53.85 mL |
| 1 mM | 2.69 mL | 13.46 mL | 26.93 mL |
| 5 mM | 0.54 mL | 2.69 mL | 5.39 mL |
*The above data is based on the productmolecular weight 371.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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