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Irbesartan(Avapro)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Irbesartan(Avapro)图片
CAS NO:138402-11-6
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议

产品名称
BMS-186295, SR-47436, Aprovel, Karvea, BMS186295
产品介绍

生物活性

Irbesartan (Avapro)是一种血管紧张素II受体拮抗剂,IC50为1.3 nM,主要用于治疗高血压。

靶点信息

AT1 receptor
1.3 nM

化学数据

目录号A10477
作用机制Antagonist (拮抗剂)
M. Wt428.5
FormulaC25H28N6O
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.138402-11-6
SynonymsBMS-186295, SR-47436, Aprovel, Karvea, BMS186295
SMILESCCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5

溶解度

In vitro (25°C)DMSOWarmed: 3 mg/mL (7 mM)
WaterInsoluble
Ethanol3 mg/mL (7 mM)
In vivo30% PEG400+0.5% Tween80+5% propylene glycol28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM23.34 mL116.69 mL233.37 mL
0.5 mM4.67 mL23.34 mL46.67 mL
1 mM2.33 mL11.67 mL23.34 mL
5 mM0.47 mL2.33 mL4.67 mL

*The above data is based on the productmolecular weight 428.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.