LDAO is a zwitterionic detergent that can be used to solubilize membrane proteins.
CAS：1643-20-5
分子式：C14H31NO
分子量：229.4
纯度：98%
存储：Store at -20°C

Background:

LDAO is a zwitterionic detergent that can be used to solubilize membrane proteins.¹It has a critical micelle concentration (CMC) of 1-2 mM. LDAO has been used to solubilize and extract colicin A from the plasma membrane and for inactivation of enveloped viruses.^1,2It has also been used in combination with 1-decanoyl-rac-glycerol (10MAG) to encapsulate proteins and nucleic acids dissolved in low viscosity fluids.³

参考文献：

1. Metola, A., Bouchet, A.M., Alonso-Marino, M., et al. Purification and characterization of the colicin A immunity protein in detergent micelles. Biochim. Biophys. Acta Biomembr. 1859(11), 2181-2192 (2017).

2. Conley, L., Tao, Y., Henry, A., et al. Evaluation of eco-friendly zwitterionic detergents for enveloped virus inactivation. Biotechnol. Bioeng. 114(4), 813-820 (2017).

3. Dodevski, I., Nucci, N.V., Valentine, K.G., et al. Optimized reverse micelle surfactant system for high-resolution NMR spectroscopy of encapsulated proteins and nucleic acids dissolved in low viscosity fluids. J. Am. Chem. Soc. 136(9), 3465-3474 (2014).