Icariin

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Icariin

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

489-32-7

包装与价格：

包装	价格(元)
50mg	电议
100mg	电议
250mg	电议
500mg	电议
10mM * 1mL in DMSO	电议

产品介绍

生物活性

Icariin对抑制PDE5A1、PDE5A2和PDE5A3的所有三种PDE5A亚型均有抑制作用，IC50值分别为1.0、0.75和1.1 μM。

靶点信息

PDE5
0.432 μM

化学数据

目录号	A10464
作用机制	Inhibitor (抑制剂)
M. Wt	676.7
Formula	C33H40O15
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	489-32-7
SMILES	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O

溶解度

In vitro	DMSO	46 mg/mL (67.98 mM)
	Water	Insoluble
	Ethanol	Insoluble
<1 mg/ml means slightly soluble or insoluble. Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.78 mL	73.89 mL	147.78 mL
0.5 mM	2.96 mL	14.78 mL	29.56 mL
1 mM	1.48 mL	7.39 mL	14.78 mL
5 mM	0.3 mL	1.48 mL	2.96 mL

*The above data is based on the productmolecular weight 676.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.