生物活性
Hydroxocobalamin是维生素B12的生物活性形式。 当以每天2 ?g的剂量连续4天给药时,在贫血的小鼠模型中,红细胞的数量比对照增加了2.5倍。
化学数据
目录号 | A10458 |
M. Wt | 1346.36 |
Formula | C62H89CoN13O15P |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 13422-51-0 |
Synonyms | Vitamin B12a |
SMILES | CC1=CC2=C(C=C1C)N(C=N2)[C@@H]3[C@@H]([C@@H]([C@H](O3)CO)OP(=O)([O-])O[C@H](C)CNC(=O)CC[C@@]\4([C@H](C5[C@]6([C@@]([C@@H](C(=N6)/C(=C\7/[C@@]([C@@H](C(=N7)/C=C\8/C([C@@H](C(=N8)/C(=C4\[N-]5)/C)CCC(=O)N)(C)C)CCC(=O)N)(C)CC(=O)N)/C)CCC(=O)N)(C)CC(=O)N)C)CC(= |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 7.43 mL | 37.14 mL | 74.27 mL |
0.5 mM | 1.49 mL | 7.43 mL | 14.85 mL |
1 mM | 0.74 mL | 3.71 mL | 7.43 mL |
5 mM | 0.15 mL | 0.74 mL | 1.49 mL |
*The above data is based on the productmolecular weight 1346.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.