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ADAMTS-5 Inhibitor
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ADAMTS-5 Inhibitor图片
CAS NO:929634-33-3
规格:98%
分子量:449.9
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) is an aggrecanase in that it cleaves aggrecan, a major proteoglycan in cartilage.
CAS:929634-33-3
分子式:C16H11ClF3N3OS3
分子量:449.9
纯度:98%
存储:Store at -20°C

Background:

A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) is an aggrecanase in that it cleaves aggrecan, a major proteoglycan in cartilage. While it has key roles in cartilage destruction associated with osteoarthritis, ADAMTS-5 is also involved in other pathways, including neurological processes. ADAMTS-5 Inhibitor is an inhibitor of ADAMTS-5 (aggrecanase-2; IC50 = 1.1 &#181M) with 40-fold selectivity over ADAMTS-4 (aggrecanase-1).