| CAS NO: | 1642288-47-8 |
| 规格: | 98% |
| 分子量: | 273.33 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 25mg | 电议 |
Background:
MYK-461 is a small molecular chemical that reduces contractility by decreasing the adenosine triphosphatase activity of the cardiac myosin heavy chain.
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MYK-461 reduced ATPase activity in a dose-dependent manner with IC50 value of 0.3 mM after treatment of mouse cardiac myofibrils. MYK-461 (>10 mM) decreased the maximal ATPase rate by
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