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Methyocarbamol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Methyocarbamol图片
CAS NO:532-03-6
包装:50mg
规格:98%
市场价:579元
分子量:241.24

产品介绍
Carbonic anhydrase inhibitor
CAS:532-03-6
分子式:C11H15NO5
分子量:241.24
纯度:98%
存储:Store at -20°C

Background:

Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms.Target: Carbonic AnhydraseMethocarbamol is the carbamate of guaifenesin, but does not produce guaifenesin as a metabolite, because the carbamate bond is not hydrolyzed metabolically; metabolism is by Phase I ring hydroxylation and O-demethylation, followed by Phase II conjugation. All the major metabolites are unhydrolyzed carbamates. Methocarbamol is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm [1, 2].


参考文献:
[1]. Bruce, R.B., L.B. Turnbull, and J.H. Newman, Metabolism of methocarbamol in the rat, dog, and human. J Pharm Sci, 1971. 60(1): p. 104-6.
[2]. Sica, D.A., et al., Pharmacokinetics and protein binding of methocarbamol in renal insufficiency and normals. Eur J Clin Pharmacol, 1990. 39(2): p. 193-4.