LAS101057是一种有效的，选择性的，可口服的A2Breceptor拮抗剂。
CAS：925676-48-8
分子式：C18H14FN5O
分子量：335.34
纯度：98%
存储：Store at -20°C

Background:

LAS101057 is a potent, selective, and orally efficacious A2B receptor antagonist.

At 3 mg/kg, LAS101057 is active in preventing methacholine-induced AHR, and at 10 mg/kg it inhibits AHR to methacholine to a level virtually equal to that seen with dexamethasone at 1 mg/kg[1].

[1]. Paul Eastwood, et al. Discovery of LAS101057: A Potent, Selective, and Orally Efficacious A2B Adenosine Receptor Antagonist. ACS Med Chem Lett. 2011 Mar 10; 2(3): 213-218.